What is clinical toxicology frank barile begins with the traditional definition the discipline within toxicology concerned with the toxic effect of agents whose intent is to treat ameliorate modify or prevent disease states or the effect of drugs which at one time were intended to be used as such. Clinical toxicology principles and mechanisms second edition crc press book examining the complex interactions associated with clinical toxicological events and chemical exposure of drug administration this updated and revised second edition functions as a stand alone text or reference of clinical toxicology for professionals students of . Preface acknowledgments contributors introduction to basic toxicological principles introduction risk assessment and regulatory toxicology therapeutic monitoring of adverse drug reactions classification of toxins in humans exposure effects dose response descriptive animal toxicity tests in vitro . Clinical toxicology principles and mechanisms barile frank a isbn 13 9781420092257 table of contents introduction to basic toxicological principles. After introducing the fundamental principles of toxicology the book presents the toxicity of therapeutic and non therapeutic agents in separate sections most chapters start with a basic review of the general physiology and pharmacology principles necessary for understanding the underlying mechanisms of toxicity the book includes numerous
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